Management of chronic obstructive pulmonary disease (COPD)

Management of chronic obstructive pulmonary disease (COPD)

 

COPD often co-exists with asthma and treatment therefore is similar.

 

COPD includes the spectrum of chronic bronchitis (sputum production on most days for 3 months of 2 consecutive years) and emphysema (dilatation of the air spaces by destruction of their walls). The two co-exist in varying proportions in COPD.

 

Clinical features are wheeze, dyspnoea, cough and sputum; if long-standing, cyanosis and cor pulmonale may be present. Assess how fit the patient is and how far he can walk on the flat.

 

CxR shows hyperinflation, flat diaphragms, large central pulmonary arteries but reduced peripheral, vascular markings, bullae.

 

Do oxygen saturation (pt may be used to low values; consider oxygen saturation together with clinical signs; if very dyspnoeic and/or cyanosed, this may indicate acute hypoxemia) and measure haematocrit to look for polycythaemia. If sputum is purulent, ask lab to perform microscopy with gram stain.

 

If pt is acutely unwell (rule out infection, left ventricular failure, sedatives, pulmonary embolism, pneumothorax; remember that abdominal problems and other infections may cause respiratory problems too):

-         administer oxygen at 2-3l/min; watch carefully not to give more oxygen as this may cause respiratory depression!!!

-         give nebulizers: salbutamol 2.5-5 mg or terbutaline 5-10 mg and! ipratropium bromide 0.5 mg

-         give prednisolone 20 mg (40 mg if already on steroids) and add hydrocortisone 100 mg i.v. if very unwell unless known to be unresponsive to corticosteroids

-         prescribe antibiotics if at least two of the following is present: increased dyspnoea, increased sputum volume and/or purulent sputum. Amoxycillin is a standard first choice.

-         as last resort try aminophylline i.v. (0.5 mg/kg/h); you cannot use this if pt has been on oral aminophylline before.

-         if pt cannot maintain the respiratory effort (he may be exhausted, drowsy, confused), consider intubation; consult a doctor.

 

On discharge aim for maximal bronchodilation with drugs (see above). Pts who have responded to nebulizers, will benefit from bronchodilatory inhalers. Show them technique and give enough supply! Give follow-up appointments and treat as indicated above.